DosedWise

Delivery technology intelligence

“Advanced delivery” is a claim until the formulation proves it.

DosedWise separates the delivery label from the evidence behind the exact technology, compound, comparator, and finished formulation.

Technologies tracked

Five systems. One standard of proof.

DosedWise will score named technologies only when enough public data exist. Until then, uncertainty stays visible.

  1. Liposomal delivery

    Formulation-specific

    Was the finished formulation actually characterized?

    The word liposomal is not proof. Particle data, encapsulation, stability, comparator, and human pharmacokinetics must support the claim.

  2. Phytosome complexes

    Formulation-specific

    Is evidence tied to the named complex or only the ingredient?

    A branded phospholipid complex can have useful evidence, but results cannot be transferred automatically to every product using similar language.

  3. Micellar systems

    Formulation-specific

    Does the comparator isolate the delivery effect?

    Solubilization may help selected compounds. The size of the advantage depends on the exact system, compound, dose, and study design.

  4. Chelated minerals

    Moderate

    Which ligand, elemental dose, and analytical verification?

    Chelated is a family, not a single technology. Identity, mineral yield, tolerability, and direct comparative evidence matter.

  5. Modified release

    Formulation-specific

    Does the release profile improve the intended outcome?

    Extended and delayed release can change exposure or tolerability, but a longer release profile is not automatically a better clinical product.

Evaluation framework

Six questions before any delivery advantage is credited.

  1. 01

    Identity

    What exact formulation or named technology was tested?

  2. 02

    Characterization

    Are particle size, encapsulation, or chemical identity documented?

  3. 03

    Stability

    Does the formulation remain intact through storage and relevant conditions?

  4. 04

    Comparator

    Was it compared with the correct conventional form at the same dose?

  5. 05

    Human PK

    Do human data support a meaningful AUC, Cmax, or exposure difference?

  6. 06

    Replication

    Has the result been reproduced independently or across studies?

Product scores remain governed by the public EDE methodology. Delivery-specific scoring will be published before it affects any verdict.

Read the current methodology